9 research outputs found

    PROPHYLACTIC EVALUATION OF SHOULDER PROPRIOCEPTION IN ELITE SWIMMERS

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    It is suggested that poor shoulder proprioception contributes to shoulder pain in swimmers. However, there is a lack of studies describing the measurement method for shoulder proprioception. The purposes of this preliminary study was to investigate the scapular position depending on arm scaption as a first step in the development of a measurement method for three-dimensional shoulder proprioception. An asymptomatic young adults participated in this study. His scapular rotation were measured as a function of arm position during scaption in two consecutive days. The results showed that scapular rotations are not a reproducible function of humerus elevation. Those findings suggested that the assessement of shoulder proprioception should rely on the evaluation of both gleno-humeral and scapulo-thoracic joints to be valid

    Research response to coronavirus disease 2019 needed better coordination and collaboration: a living mapping of registered trials

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    Objectives: Researchers worldwide are actively engaging in research activities to search for preventive and therapeutic interventions against coronavirus disease 2019 (COVID-19). Our aim was to describe the planning of randomized controlled trials (RCTs) in terms of timing related to the course of the COVID-19 epidemic and research question evaluated. Study Design and Setting: We performed a living mapping of RCTs registered in the WHO International Clinical Trials Registry Platform. We systematically search the platform every week for all RCTs evaluating preventive interventions and treatments for COVID-19 and created a publicly available interactive mapping tool at https://covid-nma.com to visualize all trials registered. Results: By August 12, 2020, 1,568 trials for COVID-19 were registered worldwide. Overall, the median ([Q1–Q3]; range) delay between the first case recorded in each country and the first RCT registered was 47 days ([33–67]; 15–163). For the 9 countries with the highest number of trials registered, most trials were registered after the peak of the epidemic (from 100% trials in Italy to 38% in the United States). Most trials evaluated treatments (1,333 trials; 85%); only 223 (14%) evaluated preventive strategies and 12 postacute period intervention. A total of 254 trials were planned to assess different regimens of hydroxychloroquine with an expected sample size of 110,883 patients. Conclusion: This living mapping analysis showed that COVID-19 trials have relatively small sample size with certain redundancy in research questions. Most trials were registered when the first peak of the pandemic has passed

    Bactériémies à Bacillus cereus en réanimation néonatale à l’AP-HP en 2016

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    International audienceIntroduction – Nine cases of Bacillus cereus bacteremia occurred in five neonatal resuscitation units (NRU) of the Assistance Publique-Hôpitaux de Paris (AP-HP) between August and December 2016. Method – The survey conducted around these cases included a study of the records to search for a common source, samples of the environment (surfaces, materials, batches of pasteurized milk, parenteral nutrition), a genetic comparison of clinical and environmental strains, a retrospective survey of AP-HP microbiology labo - ratories to estimate the incidence of B. cereus bacteremia in NRUs, and finally an evaluation of the milk circuit, from production to administration. Results – The retrospective survey showed that the incidence of B. cereus bacteremia in NRUs increased from 0.05 to 0.33 per 100 admissions between 2014-2015 and 2016. The only common point to all cases was to have received a lipid emulsion from the same manufacturer, as the majority of newborns in NRUs do. No common source contaminated by B. cereu s was identified. B. cereus was isolated from lots of pasteu - rized breast milk (two lots consumed by 2 cases and some not delivered), and some environmental samples. The comparison of the strains showed a great genotypic diversity. Improvements were implemented after evaluation of the milk circuit. Conclusion – At the end of 2016, an upsurge in the number of cases of B. cereus bacteremia was observed in five neonatal resuscitations units of AP-HP. The implication of a batch contamination of pasteurized milk has not been proven. No common source could be identifiedIntroduction – Neuf cas de bactériémie à Bacillus cereus sont survenus dans cinq réanimations néonatales (RNN) de l’Assistance publique-Hôpitaux de Paris (AP-HP) entre août et décembre 2016. Méthode – L’enquête menée autour de ces cas a inclus une étude des dossiers pour rechercher une source commune, des prélèvements de l’environnement (surfaces, matériels, lots de lait pasteurisé, nutrition paren - térale), une comparaison génétique des souches cliniques et environnementales, une enquête rétrospective auprès des laboratoires de microbiologie de l’AP-HP pour estimer l’incidence des bactériémies à B. cereus en RNN, et enfin une évaluation du circuit du lait, de la production à l’administration. Résultats – L’enquête rétrospective a montré que l’incidence des bactériémies à B. cereus en RNN avait augmenté de 0,05 à 0,33 pour 100 admissions entre 2014-2015 et 2016. Le seul point commun à tous les cas était d’avoir reçu une émulsion lipidique d’un même fabricant, comme la majorité des nouveau-nés en RNN. Aucune source commune contaminée par B. cereus n’a été identifiée. B. cereus a été isolé dans des lots de lait maternel pasteurisé (deux lots consommés par deux des cas et d’autres non délivrés) et quelques prélèvements d’environnement. La comparaison des souches a montré une grande diversité génotypique. Des améliorations ont été mises en place après évaluation du circuit du lait. Conclusion – Fin 2016, une recrudescence du nombre de cas de bactériémies à B. cereus a été constatée dans cinq réanimations néonatales de l’AP-HP. L’implication d’une contamination de lots de lait pasteurisé n’a pas été prouvée. Aucune source commune n’a pu être identifiée

    Impact of the spatial distribution of the atmospheric forcing on water mass formation in the Mediterranean Sea

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    International audienceThe impact of the atmospheric forcing on the winter ocean convection in the Mediterranean Sea was studied with a high-resolution ocean general circulation model. The major areas of focus are the Levantine basin, the Aegean-Cretan Sea, the Adriatic Sea, and the Gulf of Lion. Two companion simulations differing by the horizontal resolution of the atmospheric forcing were compared. The first simulation (MED16-ERA40) was forced by air-sea fields from ERA40, which is the ECMWF reanalysis. The second simulation (MED16-ECMWF) was forced by the ECMWF-analyzed surface fields that have a horizontal resolution twice as high as those of ERA40. The analysis of the standard deviations of the atmospheric fields shows that increasing the resolution of the atmospheric forcing leads in all regions to a better channeling of the winds by mountains and to the generation of atmospheric mesoscale patterns. Comparing the companion ocean simulation results with available observations in the Adriatic Sea and in the Gulf of Lion shows that MED16-ECMWF is more realistic than MED16-ERA40. In the eastern Mediterranean, although deep water formation occurs in the two experiments, the depth reached by the convection is deeper in MED16-ECMWF. In the Gulf of Lion, deep water formation occurs only in MED16-ECMWF. This larger sensitivity of the western Mediterranean convection to the forcing resolution is investigated by running a set of sensitivity experiments to analyze the impact of different time-space resolutions of the forcing on the intense winter convection event in winter 1998-1999. The sensitivity to the forcing appears to be mainly related to the effect of wind channeling by the land orography, which can only be reproduced in atmospheric models of sufficient resolution. Thus, well-positioned patterns of enhanced wind stress and ocean surface heat loss are able to maintain a vigorous gyre circulation favoring efficient preconditioning of the area at the beginning of winter and to drive realistic buoyancy loss and mixing responsible for strong convection at the end of winter
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